the random musings not worthy of new thread thread

MMH · February 23, 2011, 07:33:54 PM

http://economictimes.indiatimes.com/news/news-by-industry/healthcare/biotech/biotech/expect-a-global-partner-for-new-oral-insulin-in-6-mnts-biocon/articleshow/7327743.cms

I worked on this back in the 1990s. We developed a way to modify insulin so you could take it as a pill. Looks like it might finally reach the market this year. Very cool.

PhillyPhreak54 · February 23, 2011, 08:55:02 PM

Cool stuff, MMH.

reese125 · February 24, 2011, 09:14:35 AM

MMH--whats the scoop with the pill vs the inhaler?

it seems as though the problem with the pill has been that the insulin is gets broken down to quick before it gets to the bloodstream. how have you guys changed that?

ice grillin you · February 24, 2011, 10:15:31 AM

i find 99% of the internet stupid as hell but this one of the funniest things ive seen in a long time

Sgt PSN · February 24, 2011, 10:44:08 AM

Of all the things on the internet, that's part of the 1% you find funny?

smeags · February 24, 2011, 10:46:17 AM

yeah because that Hoyda cat came all thug like and all yo.

ice grillin you · February 24, 2011, 10:47:17 AM

yeah elder whites and/or tesla fans def arent feelin this

Diomedes · February 24, 2011, 10:47:57 AM

The O.G. does not approve.

Sgt PSN · February 24, 2011, 10:49:16 AM

Don't get me wrong, it's funny. I like it. But it's not "one of the funniest things I've see in a long time" funny. More like "one of the funniest things I've seen in the last 10 minutes" funny.

Diomedes · February 24, 2011, 10:50:14 AM

It would have been funnier without all caps profanity.

But yeah, it's really not that funny.

charlie · February 24, 2011, 10:56:55 AM

It would have been funnier if it were funny.

ice grillin you · February 24, 2011, 11:05:15 AM

Quote from: Sgt PSN on February 24, 2011, 10:49:16 AM
Don't get me wrong, it's funny. I like it. But it's not "one of the funniest things I've see in a long time" funny. More like "one of the funniest things I've seen in the last 10 minutes" funny.

well i have a special sense of humor that most people think sucks so maybe thats it...remember i think koq is the funniest show of all time...i also find internet humor to be abominable probably a lot more so than you

mussa · February 24, 2011, 11:07:15 AM

Lose the close up of the head and the "come at me bro" line and its a decent addition to the stupid cat pictures on the webz.

DH · February 24, 2011, 11:48:12 AM

enjoy romey

MMH · February 24, 2011, 06:32:21 PM

Quote from: reese125 on February 24, 2011, 09:14:35 AM
MMH--whats the scoop with the pill vs the inhaler?

it seems as though the problem with the pill has been that the insulin is gets broken down to quick before it gets to the bloodstream. how have you guys changed that?

The inhaler had a lot of health related issues. Insulin is a growth factor, and people using the inhaler saw hyperplasia (increased cellularity) of the lungs, which made breathing difficult.
One advantage to oral insulin is that the delivery system is the same as the natural one (dumped into the portal vein as it enters the liver). The thinking is that most of the insulin will go to the organ where it works, and prevent the high plasma levels of insulin you see with injections, hopefully leading to fewer hypoglycemic shock cases.

It wouldn't completely replace the needles. Ideally, you'd take a pill with each meal, and a shot at bedtime to get you through the night.